Cyclobenzaprine Flexeril Side Effects & Interactions

Take this medication by mouth with or without food as directed by your doctor. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Cyclobenzaprine is used short-term to treat muscle spasms. It is usually used along with rest and physical therapy.

It is generally used for musculoskeletal conditions, including fibromyalgia and low back pain. Cyclobenzaprine is best used in short-term treatment but may be used intermittently or long-term for chronic pain. The recommended dose of immediate-release cyclobenzaprine is 5 to 10mg, three times a day, while that for extended-release versions is 15 to 30 mg, once a day. Maximum daily dose for either form is 30 mg over the course of 24 hours. Taking more may result in adverse Flexeril side effects or overdose.

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Whether cyclobenzaprine is superior to other drugs for the management of acute myofascial strain is unclear and it usually adds more side effects with little therapeutic gain (Turturro et al 2003). For neck pain, however, mixed results are obtained (Peloso et al 2005). There are no extensive studies on the use of cyclobenzaprine in the management of painful orofacial musculoskeletal conditions. The results suggest that cyclobenzaprine is superior to both placebo and clonazepam when added to self-care and education for the management of jaw pain upon awakening. In this study cyclobenzaprine (10mg/d) failed to significantly improve sleep in the short term but this may have been due to the relatively low dose employed.

Talk to your care team about the use of this medication in children. If this medication upsets your stomach, take it with food or milk. If additional types of substance dependence (e.g., alcohol, opioids, sedatives) are a factor, medical detox may be needed. Do not use the extended-release capsules if you have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within 14 days of each other.

Cyclobenzaprine Dependence and Misuse Potential

Flexeril depresses the central nervous system, an effect some find desirable, which can lead to misuse. An individual might abuse Flexeril in order to feel relaxed, mildly euphoric, or sedated. Flexeril produces a variety of anticholinergic effects in high doses, altering the activity of brain neurotransmitters. Additionally, Flexeril users may experience mild withdrawal symptoms if the drug is used chronically in high doses.

Ask your healthcare professional how you should dispose of any medicine you do not use. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for flexeril tabletas which you are using the medicine. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. You might start to feel some of the effects of cyclobenzaprine within 20 to 30 minutes of taking it.

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Avoid or limit the use of alcohol or other sedating medicines while being treated with cyclobenzaprine. Also avoid driving, operating machinery, or other hazardous activities until you know how cyclobenzaprine affects you. Many treatment programs offer medical detoxification to address physical dependence in a safe environment with caring physicians and nurses who will work to alleviate symptoms and increase your comfort. There are options available across the full continuum of care to help with substance abuse.

The extended-release form typically has a half-life of hours. Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Cyclobenzaprine is usually taken taken for up to 2 or 3 weeks. RxList does not provide medical advice, diagnosis or treatment.

The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.

Call emergency for help if you have problems breathing or unusual sleepiness. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. If you have questions about side effects, call your doctor. This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.

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